CBD Oil For Rotator Cuff Pain

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A CBD tablet reduces pain after shoulder surgery without side effects sometimes associated with CBD use, such as nausea, anxiety, and liver toxicity. Your access to this site has been limited by the site owner If you think you have been blocked in error, contact the owner of this site for assistance. If you are a WordPress user with

CBD tablet safely eases pain after shoulder surgery

“There is an urgent need for viable alternatives for pain management, and our study presents this form of CBD as a promising tool after arthroscopic rotator cuff repair,” says Michael J. Alaia. (Credit: Getty Images)

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An orally absorbed tablet containing cannabidiol, also known as CBD, effectively reduces pain after shoulder surgery with no safety concerns, a new study finds.

Researchers found that the tablet ORAVEXX safely managed pain after minimally invasive rotator cuff surgery, and did not produce side effects sometimes associated with CBD use, such as nausea, anxiety, and liver toxicity.

“There is an urgent need for viable alternatives for pain management, and our study presents this form of CBD as a promising tool after arthroscopic rotator cuff repair,” says lead investigator Michael J. Alaia, associate professor in the orthopedic surgery department at New York University.

“It could be a new, inexpensive approach for delivering pain relief, and without the side effects of anti-inflammatory drugs like NSAIDs and addiction risks linked to opiates. Additionally, CBD has the benefit of pain relief without the psychotropic effects associated with THC or marijuana.”

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The multicenter phase 1/2 clinical trial randomly sorted 99 participants across two study sites (NYU Langone Health and Baptist Health/Jacksonville Orthopaedic Institute) between the ages of 18 and 75 into a placebo group and a group receiving oral-absorbed CBD.

Participants were prescribed a low dose of Percocet, instructed to wean off the narcotic as soon as possible, and to take the placebo/CBD three times a day for 14 days after the surgery.

On the first day after surgery, patients receiving CBD experienced on average 23% less pain as measured by the visual analog scale (VAS) pain score compared to patients receiving the placebo, highlighting that in patients with moderate pain, CBD may render a significant benefit.

On both the first and second days after surgery, patients receiving CBD reported 22 to 25% greater satisfaction with pain control compared to those receiving placebo. Further analysis also showed that patients receiving 50 mg of CBD reported lower pain and higher satisfaction with pain control compared to patients receiving placebo. No major side effects were reported.

While the results are promising, Alaia cautions consumers against seeking out commercialized CBD products.

“Our study is examining a well-designed, carefully scrutinized product under an investigational new drug application sanctioned by the FDA. This is currently still experimental medicine and is not yet available for prescription,” he adds.

ORAVEXX, the buccally absorbed tablet used in this study, is a non-addictive, fast-absorbing CBD composition designed to treat pain. Orcosa Inc., a life sciences company, designed and manufactured it.

Moving forward, researchers have launched a second study looking at whether ORAVEXX can specifically treat chronic pain in patients with osteoarthritis. Multiple phase 2 studies also are planned to evaluate the drug’s efficacy for other acute and chronic pain management issues and to assess the role of CBD on inflammation.

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Researchers presented the findings at the American Academy of Orthopaedic Surgeons (AAOS) 2022 Annual Meeting in Chicago. Additional coauthors are from NYU Langone Health and Baptist Health in Jacksonville, Florida.

The Jacksonville Jaguars Foundation funded the work.

Alaia reported consulting for Arthrex, JRF Ortho, and DePuy Mitek Sports Medicine, and research support from Orcosa Inc. Kevin Kaplan of Baptist Health, reported consulting for Arthrex, Inc. and holding shares in Orcosa Inc. No other disclosures were reported.

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