Water Soluble CBD Vs Oil

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Water Soluble CBD is better absorbed by the body when swallowed. When swallowed, CBD in oil form only has 10-20% bioavailability. That means if you take a 20mg dose, you might only be absorbing 2-4mg of actual CBD. In order to consume CBD oil properly, you have to hold it under your tongue, absorbing it sublingually. A recent study by researchers affiliated with Colorado State University has found that water-soluble cannabidiol products provide the best absorption of CBD, shedding new light on best practices for consumers seeking the benefits of the popular cannabinoid.

4 Reasons Water Soluble CBD is Better Than Oil

If you’ve made it far enough in your search to read this article, you’ve at least heard about water soluble CBD. Maybe you’ve seen a bottle of water infused with CBD for sale, or something like the capsules and powders we sell here at UnCanny Wellness.

But do you actually understand why water soluble CBD is better than normal CBD oil?

Most of the products available out there today are oil-based. Tinctures, creams, salves, vapes. all oil-based products. The literal CBD oil is simply an ingredient in those varying formulations.

We have to remember that this industry is very young, and it’s only a couple years ago that people were literally selling plastic syringes full of raw CBD oil. Let me tell you, that is some intensely bitter, foul tasting stuff!

Water soluble CBD is going to be a huge part of the future of CBD product development. Once you understand why it becomes clear. Here are the 4 important reasons why water soluble CBD is better than CBD oil.

1) Bioavailability

Water Soluble CBD is better absorbed by the body when swallowed. When swallowed, CBD in oil form only has 10-20% bioavailability. That means if you take a 20mg dose, you might only be absorbing 2-4mg of actual CBD. In order to consume CBD oil properly, you have to hold it under your tongue, absorbing it sublingually.

Luckily, this problem of absorption when swallowed (oral bioavailability) is relatively common in drug delivery science. Lot’s of drug compounds are naturally oil-soluble. Techniques have been developed to convert these from an oil into a format that is better absorbed in the body and easier to administer.

Using these special techniques to convert the CBD from being oil-soluble to water-soluble means that you can just swallow the CBD and your body will absorb more of it, increasing the desired effects.

2) Versatility

CBD oil can only mix in with other oils. That’s what oil-soluble means. But most of what’s out there that you’d want to incorporate CBD into is not an oil. Coffee, tea, water, juice, smoothies, dog food – all of that is going into the stomach and therefore requires a form of CBD that can be effectively absorbed in the stomach.

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If you’ve ever tried to mix CBD oil into a cup of tea, or a cocktail, you quickly find out that it doesn’t work. The oil floats to the top and sticks to the sides, it tastes terrible, and then after going through all the trouble to swallow it down you only absorb a fraction of the actual dose you’re expecting. Please don’t be that person.

3) Potency

Because CBD is more more bioavailable when swallowed than oil, it means you can take less and absorb more – it’s more potent. For example, if you swallowed a 10mg CBD oil-filled capsule you might only be absorbing 1-2mg of CBD – but if you swallowed a 10mg dose of a water soluble CBD-filled capsule you will be absorbing 9-10mg!

This is particularly important to understand when choosing the right product. So many companies out there sell cheap oil-based products at a premium just because they have high mg dosage and some shiny branding. Let’s be real, CBD products can be expensive and you deserve to get the most potent product that will work the best for you.

4) More User Friendly

If you walk into the health department of any store and you’ll see that it’s dominated by pills and powders. There might be a bit of shelf space dedicated to oil-based herbal tinctures, but people clearly prefer to consume their superfoods and supplements in pill or powder form. It’s just so much easier.

Most people out there, probably you included, would rather not hold an oil-based tincture under their tongue. It can be pretty gross tasting and isn’t very uncomfortable. Alternatively, a water soluble CBD capsule effortlessly fits into anyones existing vitamin or supplement routine. Or in powder form, you can easily infuse any of your favorite drinks and foods that you already love to consume, at whatever dose you need at that time.

At the end of the day it’s all about getting high quality CBD to more people so that they can feel b etter and live a better life. We’re all burdened with something ‘off’ from time to time, whether it’s feeling overwhelmed with the state of the world, muscle soreness after a workout or aching joints from a long life well lived.

Using the the right quality products is key to supporting your self and your loved ones, and water soluble CBD products are more effective and easier to use than CBD oil products.

New Study Suggests Water-Soluble Cannabidiol Products Provide Best CBD Absorption

A recent study by researchers affiliated with Colorado State University has found that water-soluble cannabidiol products provide the best absorption of CBD, shedding new light on best practices for consumers seeking the benefits of the popular cannabinoid. The study, which was published last month in the peer-reviewed journal Nutrients, also explored the effects that cannabidiol has on digestion and determined that CBD products are best consumed with food for maximum absorption, among other findings.

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The research, which was conducted in conjunction with Colorado State University’s Department of Health and Exercise Science, compared the absorption of five different CBD formulations in 14 male test subjects. Products studied included CBD diluted in medium-chain triglycerides (MCT) coconut oil, CBD isolate, and three different water-soluble CBD ingredients. The goal of the study was to document how each of these formulations of CBD entered and left the bloodstream and at what rate. Additionally, the study profiled how the formulations interacted with liver functionality and if there was evidence that food intake and metabolism were affected by the products.

New research shows that taking water-soluble cannabidiol products with food provided the best . [+] absorption of CBD.

Water-Soluble CBD Had Best Absorption

The study found that water-soluble CBD preparations displayed superior pharmacokinetics compared to oil-based CBD. One of the water-soluble CBD preparations used in the study was created using proprietary technology from NextEvo Naturals, which has proven to significantly improve bioavailability. John McDonagh, CEO of the company, said that the research sheds new light on how consumers can get the most out of the CBD products they take.

“While the potential health benefits of CBD have been widely publicized, this new data suggests consumers should be very aware of the pharmacokinetic differences between commercial CBD formulations, for example, how the CBD you are taking gets absorbed into the body,” McDonagh said in a statement from NextEvo. “We set out to prove that our product formulations may actually be able to offer the many benefits of CBD because they enter the bloodstream quickly and efficiently.”

The results of the study, which NextEvo notes have not been evaluated by the U.S. Food and Drug Administration, show a more than 500% variance in maximum blood concentration achieved between water-soluble CBD ingredients compared to oil-based formulations and unformulated CBD isolate. The variance represents a significant difference in the body’s ability to absorb and process CBD, which is necessary to reap the potential health and wellness benefits of the cannabinoid.

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Taking CBD With Food Increases Absorption

The results also showed that consuming water-soluble CBD with food greatly increases the body’s absorption of CBD and modifies early insulin and triglyceride responses. Six hours after consumption, CBD concentration in the bloodstream was three times higher when consumed with food compared to taking the product after fasting. David Chernoff, MD, chief medical officer at NextEvo, says that the research revealed CBD’s potential positive effect on insulin and triglyceride levels.

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“Our study results show that within 30 minutes after eating a meal, CBD appeared to lower insulin and triglyceride levels. The exact mechanism of how CBD impacts insulin levels and triglyceride levels is unclear as the CBD levels 30 min post-meal are very low,” Chernoff writes in an email. “What one can infer from these findings is that CBD may have a favorable effect on how fats and sugars are metabolized after a meal so CBD might be beneficial for supporting healthy glucose and lipid metabolism.”

Researchers have long debated if eating a meal or fasting could affect CBD’s absorption into the bloodstream. Some have found that it helps to eat when taking oil-soluble CBD, but the new research suggests that taking water-soluble CBD products with food will provide the most benefit.

“We’ve found that the best way for consumers to take CBD is in a product containing a water-soluble formulation with a meal. This allows the body the opportunity for maximum absorption into the bloodstream,” writes Chernoff. “The more CBD the body absorbs, the more likely the consumer is to experience CBD’s potential benefits.”

CBD is available in a variety of product formulations.

“This is one of the first studies to examine the potential benefits CBD has on digestion and whether it should be administered with food,” NextEvo wrote in a statement about the research. “The study provides significant evidence that consuming CBD with food alters the dynamics of CBD metabolism and increases systemic availability, favorably modifying early insulin and triglyceride responses.”

The research also revealed new evidence on the safety of CBD. The study showed that CBD taken at average doses, in this case, 30mg per dose, does not evoke physiologically relevant changes in markers of liver function, suggesting that CBD probably does not represent a risk to the liver.

Potential limitations of the study identified by the researchers include a small sample size and the fact that all test subjects were male, although the authors wrote that they “have no reason to suspect the potential for sex differences.”

A report on the study, “Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function,” was published online by the journal Nutrients in May.

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